Isle of Palms Rentals

Compare 62 vacation rentals.
USA > South Carolina > Isle of Palms

Make Isle of Palms your next getaway

Looking for a peaceful getaway to South Carolina’s sandy beaches? Our Isle of Palms vacation rentals offer tranquility, set apart from the hustle and bustle, but still close enough to enjoy the charm of Charleston. Whether you're looking for family fun or a romantic escape, the Isle of Palms has something for everyone.

Explore Isle of Palms house rentals, villas, condo rentals, and more

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House rentals

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Villas

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Condo rentals

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Isle of Palms vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
3 on 28th Unit A
3 Bed | 1.5 Bath | Sleeps 6

3 on 28th Unit A - Isle of Palms, SC

$327 avg / night
3.5 (6)
Sea Cabin 337-C
1 Bed | 1 Bath | Sleeps 4

Sea Cabin 337-C - Isle of Palms, SC

$343 avg / night
3.8 (5)
Tidewater H-202
2 Bed | 2 Bath | Sleeps 4

Tidewater H-202 - Isle of Palms, SC

$389 avg / night
4.28 (76)
Seagrove Villa 1B
2 Bed | 2 Bath | Sleeps 6

Seagrove Villa 1B - Isle of Palms, SC

$545 avg / night
4.48 (44)
Sea Cabin 306-A
1 Bed | 1 Bath | Sleeps 6 (4 Adults Max)

Sea Cabin 306-A - Isle of Palms, SC

$275 avg / night
4.51 (39)

View 57 more homes

Recent Isle of Palms vacation rental reviews

Location on the beach was wonderful. Enjoyed the deck more than any other part of the condo. It had an amazing view of the ocean. Unit was laid out well and had everything we needed. Mattress in master bedroom was so comfortable. Slept like a baby!
Jane B. | Nov 2024
Nice accommodations conveniently located just off the beach pool bar area. The house has 4 floors that provides lots of room but was challenging for the older folks in the party.
James B. | Nov 2024
Could not get the TV to work and there were no instructions to operate it. There ants all over the kitchen area. Great location.
Brian H. | Nov 2024
Isle of Palms Frequently Asked Questions

Yes, 29 of our Isle of Palms homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 115 of our Isle of Palms vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Isle of Palms vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Isle of Palms team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Isle of Palms, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning

Explore Isle of Palms, SC

Nestled on a beautiful barrier island, Isle of Palms is just 18 miles from Charleston and about 130 miles from Columbia. This idyllic location is perfect for beachgoers and nature lovers alike. The island's long stretches of beach are home to sea turtles, and if you’re lucky, you might witness local professionals helping these tiny creatures make their way to the ocean.

Things to do in Isle of Palms, SC

From beach fun to exploring nearby islands, there's no shortage of activities to enjoy during your stay.

Where is Isle of Palms, SC?

Located just off the coast of South Carolina, Isle of Palms is a barrier island near Charleston. It offers easy access to both the serene beauty of the ocean and the vibrant culture of Charleston, making it an ideal spot for vacationers looking to experience the best of both worlds.

Book an Isle of Palms vacation rental

Whether you're visiting for the beaches, the history, or just to unwind, our Isle of Palms vacation rentals provide the perfect retreat. With a range of homes featuring ocean views, spacious patios, and family-friendly amenities, you're sure to find a spot that fits your getaway vision. Browse our collection of Isle of Palms vacation homes and get ready for a relaxing escape on South Carolina’s coast.