Edisto Island Vacation Rentals

Compare 115 vacation rentals.
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USA > South Carolina > Edisto Island

Make Edisto Island your next getaway

Craving the coast? Edisto Island vacation rentals are your ticket to unspoiled natural landscapes and pristine beaches, not to mention the South Carolina charm. Chase the sunshine down south.

Explore Edisto Island house rentals, condo rentals, duplexes, and more

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House rentals

View 86 House rentals
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Condo rentals

View 18 Condo rentals
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Duplexes

View 6 Duplexes

Explore more vacation rental amenities in Edisto Island

Pool | Electric vehicle charger | Lake view | Lakefront | Ocean view | Oceanfront | Riverfront | Sound view | Soundfront | Water view

Edisto Island vacation rentals for every getaway

Popular
Dog-friendly Hot tub Internet
Sea La Vie
0 Bed | 1 Bath | Sleeps 2

Sea La Vie - Edisto Beach, SC

$193 avg / night
4.75 (16)
Sea Sea Rider
3 Bed | 3 Bath | Sleeps 6

Sea Sea Rider - Edisto Beach, SC

$345 avg / night
4.67 (30)
Sunrise, Sunset
4 Bed | 2 Bath | Sleeps 13

Sunrise, Sunset - Edisto Beach, SC

$1,286 avg / night
4.45 (184)
Driftwood Villa 270 - Sand Trap
1 Bed | 1 Bath | Sleeps 4

Driftwood Villa 270 - Sand Trap - Edisto Beach, SC

$236 avg / night
4.9 (20)
Mermaid Cottage
2 Bed | 2 Bath | Sleeps 6

Mermaid Cottage - Edisto Beach, SC

$333 avg / night
4.35 (92)

View 110 more homes

Recent Edisto Island vacation rental reviews

Loved everything about this house! Comfy beds, wonderful view of ocean being across the street from the beach, great layout of the house and little extras like soaps, shampoos etc. Have rented from Vacassa 4 times and have had great experiences with this company.
Lynda H. | Mar 2025
Beautiful location and great house!
Rebecca R. | Mar 2025
This vacation home met all of our get-away needs! Good location, quiet and private with a pleasant walk to the beach. The furniture was comfortable, including the beds. The kitchen had everything we needed for cooking meals. The week flew by! We plan to stay here again.
Nancy T. | Mar 2025
Edisto Island Frequently Asked Questions

Yes, 45 of our Edisto Island homes allow dogs—so feel free to bring Fido along. (Just make sure to check individual home listings for any limits on the number and size of dogs they allow).

Browse dog-friendly homes >

Yes. 115 of our Edisto Island vacation rentals have internet access, so you can stay connected throughout your trip.

Browse homes with internet access >


Some of the most popular amenities in our Edisto Island vacation rentals include:

Our standard check-in time is 4:00 p.m., and the check-out time is 10:00 a.m. Some exceptions apply—after you book, you’ll find check-in and check-out details in the Vacasa guest app or your Trip Manager.

Absolutely. Our local Edisto Island team includes professional housekeepers who care for all our homes here. They’ll clean thoroughly and restock amenities, so everything is ready for your arrival—and all you have to do is settle in and relax.

Learn more about Vacasa Premium Clean >

No worries, plans change. Read over our cancellation policy for more information. And if you currently have a Vacasa reservation for Edisto Island, log in to Trip Manager to see options available for your specific trip.

Book confidently. Stay comfortably.

Book confidently. Stay comfortably.
24/7 support
Easy check-in
Easy check-in
Professional cleaning
Professional cleaning


Explore our Edisto Island, SC vacation rentals

Uncommercialized and family-friendly, Edisto Island offers travelers a chance to experience the tranquility, scenic beauty, and wildlife of the southeastern coast. The area is surrounded by protected nature reserves, meaning turtle, dolphin, and various marine bird sightings are never too hard to come by. Kayak through the meandering rivers, plan a stroll through scenic Botany Bay, or tour the Edisto Island Serpentarium.

Find an Edisto Island beachfront rental and never stray too far from the ocean. Though you can immerse yourself in the coastal environment, Charleston is only an hour away if you’re looking for a day trip for city attractions. Bring family and friends to the beach for a southern adventure.

People also search for

Edisto Beach   |   Edisto Island   |   South Carolina
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